Andrzej Polanczyk
Medical University of Vienna, Austria
Title: A new approach for blood hemodynamic reconstruction in human vessels with a new artificial circulatory model
Biography
Biography: Andrzej Polanczyk
Abstract
Introduction: The aim of the study was to investigate a mechanical behavior of various types of artificial vessels in relation to the iliac arteries with the use of dedicated ex vivo bioengineering reactor.
Methods: Artificial circulatory model (ACM) for computational projection of vessel structure under different flow conditions was designed and built. Analyzed vessels were supplying with the homemade fluid mimicking blood. Following types of vessels were analyzed: synthetic prostheses (ePTFE, ePTFE with spiral, Dacron), biosynthetic prostheses (Omniflow II, gelatin sealedePTFE), iliac arteries and silicon tubes. Each time the same length of vessel (100 mm) was analyzed. Mechanical behavior was introduced with the use of following parameters: change of diameter, wall displacement, deformation factor and divergent factor. Moreover, ACM results were verified with medical data. 2D-speckle-tracking-technique (2DSTT) was applied to assess diameter dilatation for patients with ePTFE prostheses/iliac arteries.
Results: It was presented that both Dacron and bio prostheses act similarly to real tissue. Approximately 21% difference for gelatin sealed ePTFE prostheses and 25% for Dacron prostheses compare to iliac arteries was observed. While, ePTFE prostheses presented about 2.4-fold increase of stiffness compare to the flexibility of iliac arteries. Moreover, ePTFE prostheses act much more like silicon tubes rather than iliac arteries.
Conclusions: Artificial reconstruction of blood flow in different spatial configuration of human and artificial vessels allows simulating different mechanical response of tissue vascular grafts and silicon tubes.